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By [http://ezinearticles.com/?expert=Robert_McKay] Robert McKay Introduction There are many drugs that have had recalls associated with them because of side effects that were unforeseen and Permax is one of these drugs. Permax, also known as pergolide in the generic sense, was a drug that had been used by millions of people across the world to treat their Parkinsons disease. It is not a cure for Parkinsons disease but rather is a treatment that was developed in order to help patients deal with some of the symptoms of Parkinsons disease. A disease that is similar to Parkinsons known as Ekboms syndrome or simply as restless leg syndrome was also treated with Permax. Between the sufferers of these two illnesses the Permax drug became very popular as a treatment until it was discovered that there were some adverse side effects to using the drug as a treatment. How Permax Works This is best demonstrated using an example. Parkinsons disease is caused by a breakdown within the central nervous system that is ultimately linked to a malfunctioning motor cortex. This malfunctioning motor cortex is not being stimulated at a level that allows the individual to have normal motor skills as well as normal speech. The reason for the lack of stimulation is that the stimulation occurs through the usage of a substance known as dopamine. Dopamine is a neurotransmitter that is used for this specific purpose and when there is a lack of dopamine in the system there are going to be problems with the motor processes. Permax as a drug has the ability to mimic dopamine and help restore some of that missing stimulation. This in turn will allow the individual the chance to perform with a higher level of motor skills and thus counteract to a certain extent the symptoms of their illness. It is this ability that originally resulted in Permaxs popularity up until the point where the negative effects associated with the drug were made public. The Problem with Permax The positive effects of Permax notwithstanding, there are a number of negative [http://www.schmidtandclark.com/Permax/side-effects-recall.html ] side effects that have severely decreased the popularity of the drug. Two different independent studies began the discovery by linking all pergolide drugs with different side effects related to heart valves. Heart valves are the parts of the heart that regulate the blood flow into and out of the organ as well as between the different chambers of the organ. One study found that Permax dramatically increased the chance of severe damage to these heart valves and another study found that a significant number of patients that had taken Permax or a similar pergolide drug suffered from leaky heart valves. A leaky or otherwise damaged heart valve can result in severe complications in blood flow around the body which can lead to other problems such as pulmonary hypertension, severe lethargy, poor blood flow to the extremities and even muscle death from lack of oxygenated blood. Ever since these two studies were released the popularity of Permax has been on the decline and as of right now the popularity of the drug is significantly lower than it was a few years ago. Do I Have a Permax Lawsuit? Schmidt & Clark | A National Law Firm, specializing in mass torts and drug side effect lawsuits. The law firm is handling Permax (Pergolide) lawsuits in all 50 states For more information about Schmidt & Clark, please visit: [http://www.schmidtandclark.com/ ] http://www.schmidtandclark.com For more detailed information about Permax (Pergolide) Side Effects or Recall Lawsuits, please visit our: [http://www.schmidtandclark.com/Permax/ ] Permax Recall Resource Article Source: [http://ezinearticles.com/?expert=Robert_McKay ] http://EzineArticles.com/?expert=Robert_McKay [http://ezinearticles.com/?What-is-Permax-(Pergolide)?&id=541227 ] http://EzineArticles.com/?What-is-Permax-(Pergolide)?&id=541227 phentermine no prescription overnight delivery cheap phentermine without perscription buy phentermine master card can i buy phentermine online